Sherlock Holmes, the world’s most famous “consulting detective,” holds a unique place in the culture of Mayo Clinic. Only one of the statements below is correct. But which one is it? As Holmes would say, “The game is afoot.”

A. On a trip to England, Dr. Charles Mayo met Dr. Arthur Conan Doyle, the physician-author who created the character of Sherlock Holmes. They struck up a friendship and corresponded for many years.

B. Dr. Henry Plummer wrote a landmark article for “Mayo Clinic Proceedings” that compared the discipline of medical research to the process of deductive reasoning that Sherlock Holmes used in solving his cases.

C. Dr. Philip Hench, one of two Mayo staff members who received the Nobel Prize for discovering cortisone, was an avid collector of Sherlock Holmes memorabilia.

D. In the 1997 film adaptation of the classic Sherlock Holmes mystery, “The Hound of the Baskervilles,” Holmes’ companion, Dr. John Watson, tells a patient, “Only the Mayo Clinic can help you now.”